學習經歷
2005-2009 河北農業大學,學士
2009-2012 中國農業科EON4,碩士
2012-2017 中國科EON4,博士
工作經歷
2017-2019 首都師範大學EON体育4注册,博士後
2019- EON体育4登录,教授
榮譽稱號及社會兼職
太行學者二層次人才🐵,河北省優秀青年基金獲得者👩👩👧👧,河北省教育廳青年拔尖人才
aBIOTECH期刊青年編委
教學工作(本科生、研究生)
本科生課程:
1. 專業基礎課《植物生理學》
2. 專業選修課《生態學》
研究生課程:
1.《現代生物技術與方法》
2.《高級發育生物學》
3.《高級植物生理學》
主持課題項目
1.國家自然科學基金,基於CRISPR/Cas9技術解析γ-氨基丁酸調控大白菜耐熱性的分子機製,2025-2027,32402564,主持
2.河北省自然科學基金😒,高效腺嘌呤堿基編輯體系的建立及其在創製富含蘿蔔硫苷大白菜中的應用研究,2023-2025,C2023204119,主持
3.河北省省級科技計劃專項,植物基因組無PAM序列限製的CRISPR/Cas9編輯體系的建立及應用😝,2021-2023,21372901D,主持
4.河北省教育廳青年拔尖人才計劃項目👩🏽🦲,MAC3A和MAC3B調控擬南芥雄配子體發育的研究,2021-2023,BJ2021025👷🏿,主持
5.河北省優秀青年科學基金,組蛋白H2B單泛素化修飾參與小立碗蘚環境適應的機製研究,2020-2022👨🏽🎤,C2020204062,主持
6.EON体育4人才引進項目,小立碗蘚H2B單泛素化的研究,2019-2024,YJ201958,主持
代表性學術成果
研究論文(*通訊作者)🦹🏼:
1.Shan Q1, Wang Y1, Li J1, Zhang Y, Chen K, Liang Z, Zhang K, Liu J, Xi J, Qiu J, Gao C* (2013) Targeted genome modification of crop plants using a CRISPR-Cas system. Nature Biotechnology, 31, 686-688.(共同第一作者,中科院一區top)
2.Li J, Meng X, Zong Y, Chen K, Zhang H, Liu J, Li J*, Gao C* (2016) Gene replacements and insertions in rice by intron targeting using CRISPR/Cas9. Nature Plants, 2, 16139.(第一作者🎯👨❤️💋👨,中科院一區top)
3.Li J, Zhang H, Si X, Tian Y, Chen K, Liu J, Chen H, Gao C* (2017) Generation of thermosensitive male-sterile maize by targeted knockout of the ZmTMS5 gene. Journal of Genetics and Genomics, 44, 465-468.(第一作者,中科院二區)
4.Li J, Li Y, Ma L* (2019) CRISPR/Cas9-based genome editing and its applications for functional genomic analyses in plants. Small Methods, 3, 1800473.(第一作者,中科院一區)
5.Li J, Yang J, Li Y, Ma L* (2020) Current strategies and advances in wheat biology. The Crop Journal, 8, 879-891.(第一作者,中科院一區)
6.Li J, Li Y, Ma L* (2021) Recent advances in CRISPR/Cas9 and applications for wheat functional genomics and breeding. aBIOTECH, 3, 1800473.(第一作者,中科院四區)
7.Li Y, Li WJ, Li J* (2021) The CRISPR/Cas9 revolution continues: from base editing to prime editing in plant science. Journal of Genetics and Genomics, 48, 661-670.(通訊作者🖥,中科院二區)
8.Li J*, Yu X, Zhang C, Li N, Zhao J* (2022) The application of CRISPR/Cas technologies to Brassica crops: current progress and future perspectives. aBIOTECH, 3, 146–161.(第一兼通訊作者,中科院四區)
9.Zhang C, Wang D, Li W, Zhang B, Abdel-Fattah Ouf GM, Su X*, Li J* (2022) The coat protein p25 from maize chlorotic mottle virus involved in symptom development and systemic movement of tobacco mosaic virus hybrids. Frontiers in Microbiology, 13,951479. (通訊作者🤽🏼♀️,中科院二區)
10.Zhang C, Liu S, Li X, Zhang R, Li J* (2022) Virus-Induced Gene Editing and Its Applications in Plants. International Journal of Molecular Sciences. 23, 10202.(通訊作者,中科院二區)
11.Zhang K, Liu S, Fu Y, Wang Z, Yang X, Li W, Zhang C, Zhang D, Li J* (2023) Establishment of an efficient cotton root protoplast isolation protocol suitable for single-cell RNA sequencing and transient gene expression analysis. Plant Methods. 19, 5.(通訊作者,中科院二區)
12.Yu X, Huo G, Yu J, Li H, Li J* (2023) Prime editing: Its systematic optimization and current applications in disease treatment and agricultural breeding. International Journal of Biological Macromolecules. 253, 127025.(通訊作者,中科院一區)
13.Li W, Li X, Wang C, Huo G, Zhang X, Yu J, Yu X, Li J, Zhao J, Li Y, Li J* (2024) Expanding the targeting scope of CRISPR/Cas9-mediated genome editing by Cas9 variants in Brassica. aBIOTECH, 5, 202–208.
14.Yu X, Yu J, Lu Y, Li W, Huo G, Zhang J, Li Y, Zhao J, Li J* (2024) An efficient and universal protoplast-based transient gene expression system for genome editing in Brassica crops. Horticultural Plant Journal, 10, 983-994.(通訊作者🫥,中科院一區)
15.李君,張毅,陳坤玲,單奇偉,王延鵬🍊,梁振,高彩霞*. CRISPR/Cas系統:RNA靶向的基因組定向編輯新技術. 遺傳, 2013, 35, 1265-1273. (第一作者)
16.劉善賀, 潘延雲, 李君* (2023) 組蛋白H2B單泛素化在植物生長發育和脅迫應答中的作用. 農業生物技術學報. 31, 1064-1073.(通訊作者)